From Health Imaging: Reduction of contrast dosage by 25 percent or more on CT scans results in reduced low-contrast spatial resolution and loss of detection of 6mm nodules on accreditation phantoms using iterative reconstruction (IR) techniques, according to results published online March 26 in the journal Radiology.

Advancements in IR have made the technology an attractive alternative to traditional full-dose filtered back projection on CT due to its ability to substantially reduce noise and maintain high-contrast spatial resolution. The same cannot be said for IR when used to image low-contrast objects such as liver lesions or certain regions of the brain, according to lead author Cynthia McCollough, PhD, and her colleagues at the Mayo Clinic in Rochester, Minn.

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