This paper introduces and characterizes the performance of a 250-micron slice thickness acquisition mode. Noise and spatial resolution equivalent to the ultra high resolution mode on a conventional Siemens CT system can be achieved using half the radiation dose. This work was performed using a service mode implementation.
Using vials of iodine of known concentrations and various sizes of water phantoms, the accuracy of CT numbers in virtual monoenergetic images and iodine concentration in iodine maps were assessed for the Flash, Force and CounT systems.
Iodine, gadolinium, and bismuth were imaged within an animal model using a photon-counting CT system and material decomposition was performed to calculate the concentration of contrast-agents and demonstrate tissue enhancement in multiple phases for a single acquisition.
Image domain material decomposition was performed using a novel iterative denoising algorithm that uses prior information from the low-energy threshold images to reduce errors in material decomposition.
A novel multi-energy nonlocal means (MENLM) algorithm is described that uses redundancies in spatio-spectral features to reduce noise by up to 80% while maintaining spatial resolution, shape of the noise-power-spectrum, and CT number accuracy.