The CT Clinical Innovation Center is supported by extramural funding from the National Institutes of Health, philanthropic foundations, professional societies and industry partners, including a research grant from Siemens Healthcare.

Intramural funding comes from the Mayo Clinic Department of Radiology, Mayo Clinic Institutional Research Committee, the Discovery Translation Program, and the Center for Clinical and Translational Science.

Federally-Funded Grants

NIH R01 (EB028590)

Cynthia H. McCollough, Ph.D., & Shuai Leng, Ph.D., principal investigators
"Comprehensive characterization of coronary atherosclerotic disease using photoncounting-
detector dual-source CT and its impact on patient management"

NIH U24 (EB028936)

Lifeng Yu, Ph.D., principal investigator
"Dissemination of a software platform for efficient CT radiation dose optimization and diagnostic performance assessment"

NIH R01 (EB017095)

Cynthia H. McCollough, Ph.D., principal investigator
"Trade-offs in human observer performance, image quality metrics, and patient dose"

NIH R01 (EB028591)

Cynthia H. McCollough, Ph.D., principal investigator
"Quantitative, non-invasive characterization of urinary stone composition and fragility using multi-energy CT and machine learning techniques"

NIH R01 (AR071338)

Kristin D. Zhao, Ph.D., principal investigator
"4DCT Imaging for improved diagnosis and treatment of wrist ligament injuries"

NIH R42 (DK104580)

J.G. Fletcher, M.D., principal investigator of subaward (B. Yeh, PI)
STTR grant with Nextrast, Inc.
"Augmenting Dual Energy CT for Novel Contrast Agents"

Intramural and Foundation Awards

Helmsley Foundation Award

J.G. Fletcher, M.D., principal investigator
"Natural History Study, Crohn's Stricture Index, and Prospective Response"

Mayo Clinic Discovery Translation Award

Cynthia H. McCollough, Ph.D., principal investigator
"Multi-kernel image synthesis using a deep convolutional neural network"

Mayo Clinic - Arizona State University
Team Science Grant

Cynthia H. McCollough, Ph.D., principal investigator, Mayo Clinic
Williams S. Graves, Ph.D., principal investigator, Arizona State University
"Phase contrast imaging using a compact x-ray light source"

Industry Partnership

The CT Clinical Innovation Center was established in 2004 in partnership with Siemens Healthcare, a leading manufacturer of medical imaging systems. The partnership between Mayo Clinic's Department of Radiology and Siemens Computed Tomography Division allows Mayo Clinic investigators and Siemens scientists to work together to develop new technologies, clinical applications and imaging strategies to improve patient care.

To avoid real or perceived conflicts of interest, the relationship between Mayo Clinic and Siemens is managed by Mayo Clinic's Office of Medical-Industry Relations, Office of Conflict of Interest Review, and Mayo Clinic Ventures. Mayo Clinic faculty who participate in Siemens-sponsored projects are prohibited from accepting any honorarium or consulting fees. Industry support is disclosed in any presentations and publications involving Siemens-sponsored research.

Mayo Clinic does not endorse commercial products, and its collaboration with Siemens Healthcare should not be interpreted as such.

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